Technical Posters with XF Data

• Aging & Cell Physiology

  • The homeobox protein Prox1 is a negative modulator of ERRα/PGC-1α bioenergetic functions

    Alexis Charest-Marcotte, Catherine R. Dufour, Brian J. Wilson, Annie M. Tremblay, Lillian J. Eichner, Daniel H. Arlow, Vamsi K. Mootha, and Vincent Giguère; McGill University, Massachusetts General Hospital, Broad Institute
    Nuclear Receptor: Development, Physiology and Disease Conference
    March 21-26, 2010
    Keystone, Colorado

  • Testing modulators of uncoupling protein (UCP) function in intact HEK293 cells using plate-based respirometry and membrane potential sensitive fluorescent probes.

    Martin Jastroch, Akos A. Gerencser, and Martin D. Brand
    Buck Institute for Age Research
    Molecular & Cellular Bioenergetics Gordon Research Conference
    June 10, 2009
    Andover, NH

• Cancer

  • Metabolic Dependency on Fatty Acid Oxidation of Glioblastoma SF188 Cells

    Lisa S. Pike, Denise Chen, David A. Ferrick, and Min Wu; Seahorse Bioscience
    Keystone Conference Metabolism and Cancer Progression
    March 12-17, 2010
    Vancouver BC

  • Cells addicted tp BCL-XL accumulate succinate via pyruvate carboxylase metabolism and glutaminolysis.

    Daciana Margineantu and David Hockenbery, Human Biology and Clinical Research Divisions, Fred Hutchinson Cancer Research Center
    AACR Metabolism & Cancer Conference
    September 13-16, 2009
    La Jolla, CA

  • Bioenergetic differences in breast cancer cell lines

    Dilshan S. Harischandra and David Hockenbery, Iowa State University and Fred Hutchinson Cancer Research Center
    AACR Metabolism & Cancer Conference
    September 13-16, 2009
    La Jolla, CA

  • 2-Deoxyglucose Induces a Metabolic Switch to Mitochondrial Oxidative Energy Metabolism Resulting in Sensitization to Apoptosis of Glioblastoma Cells

    2006 Gordon Research Conference on Cell Death
    September 10-15, 2006
    Big Sky Resort
    Big Sky, MT

  • Real-time Metabolic Analysis of Glioblastoma Cells Treated with 2-Deoxyglucose Reveals a Metabolic Switch to Aerobic Energy Metabolism Mediated by HIF-1a

    AACR 2006 Annual Meeting
    April 1, 2006
    Washington, DC

  • A Novel Assay for Profiling Metabolic Changes Mediated by HIF-1a in Cancer Cells

    Tumor Metabolism Summit
    September 19, 2005
    Genoa, Italy

  • A Non-destructive, Time-resolved, Multi-analyte Technology for Sensing Metabolic Changes in Cancer Cells

    American Association for Cancer Research
    April 19, 2005
    Anaheim, CA

• Cardiovascular

  • Inhibition of Apoptosis Partially Restores Mitochondrial Function

    Gloria A. Benavides, Blake R. Zelickson, Sarah A. Owusu, Samantha Giordano, Lonnie Schneider, Brian Benoit, Jianhua Zhang and Victor M. Darley-Usmar, Department of Pathology, Center for Free Radical Biology, University of Alabama at Birmingham and Seahorse Bioscience.
    5th International Conference of Neurons and Brain Disease
    June 29- July 1. 2010; Bristol, England

  • Hypoxia/Reoxygenation Alters Mitochondrial Function in Endothelial Cells

    Blake R. Zelickson, Gloria A. Benavides, Aimee Landar, Jianhua Zhang, and Victor M. Darley-Usmar, Department of Pathology, Center for Free Radical Biology, University of Alabama at Birmingham
    5th International Conference of Neurons and Brain Disease
    June 29- July 1. 2010; Bristol, England

  • Bioenergetics changes induced by hydrogen peroxide exposure in endothelial cells

    Gloria A. Benavides, Brian P. Dranka, Brian Benoit, and Victor M. Darley-Usmar, University of Alabama at Birmingham and Seahorse Bioscience
    Society for Free Radical Biology's 16th Annual Meeting
    November 18 - 22, 2009
    San Francisco, California

  • 4-Hydroxy-2-Nonenal Alters Cellular Bioenergetics in Vascular Smooth Muscle Cells

    Blake R. Zelickson, Anne R. Diers, Bradford G. Hill, Brian P. Dranka, Jessica Perez, Aimee Landar, and Victor M. Darley-Usmar, University of Alabama at Birmingham
    Society for Free Radical Biology's 16th Annual Meeting
    November 18 - 22, 2009
    San Francisco, California

  • Direct measurement of bioenergetic stress in cardiomyocytes exposed to hydrogen peroxide and protection by O-GlcNAc

    Brian P. Dranka, Bradford G. Hill, Luyun Zou, John C. Chatham, and Victor M. Darley-Usmar, University of Alabama at Birmingham
    Society for Free Radical Biology's 15th Annual Meeting
    November 16 - 26, 2008
    Indianapolis, Indiana

• Hepatobiology & In Vitro Toxicity

  • In vitro detection of pharmaceutical compounds that disturb mitochondrial functions

    Irene Edebert, Ingalill Rafter, Ian Cotgreave; Molecular Toxicology, Safety Assessment, AstraZeneca R&D
    46th Congress of the European Societies of Toxicology
    September 13-16, 2009
    Dresden, Germany

• Neurodegeneration

  • Real-time monitoring of mitochondrial and cellular bioenergetics in cultured neurons in a microplate

    Neuroscience 2008
    Society for Neuroscience 38th Annual Meeting
    November 15-19, 2008
    Washington, D.C.

• Obesity, Diabetes, & Metabolic Diseases

  • The homeobox protein Prox1 is a negative modulator of ERRα/PGC-1α bioenergetic functions

    Alexis Charest-Marcotte, Catherine R. Dufour, Brian J. Wilson, Annie M. Tremblay, Lillian J. Eichner, Daniel H. Arlow, Vamsi K. Mootha, and Vincent Giguère; McGill University, Massachusetts General Hospital, Broad Institute
    Nuclear Receptor: Development, Physiology and Disease Conference
    March 21-26, 2010
    Keystone, Colorado

  • Glucose availability modulates mitochondrial sources of NADPH in skeletal muscle cells: Implications for oxidative stress

    Ryan J. Mailloux and Mary-Ellen Harper, University of Ottawa
    Charleston Conference on Mitochondrial Physiology and Pathobiology
    November 16, 2009
    Isle of Palms, North Carolina

  • β-Adrenergic and cAMP-Stimulated Mitochondrial Uncoupling in Human Adipocytes

    Einav Yehuda-Schnaidman, Naresh Kumar, Ben Buehrer, Sheila Collins, Hamner Institute
    69th Scientific Sessions of the American Diabetes Association
    June 5-9. 2009
    New Orleans, Louisiana

  • Metformin-Induced Inhibition of Mitochondrial Complex I Activity Stimulates Fatty Acid Oxidation and Glycolysis While Blunting Glucose Oxidation in C2C12 Myocytes

    Molecular & Cellular Bioenergetics
    June 17, 2007
    Andover, New Hampshire

  • A Novel, Non-Radioactive Method for Measuring Fatty Acid Oxidation and Cellular Metabolism in C2C12 Myocytes

    Endocrine Society 2006 Annual Meeting
    June 24, 2006
    Boston, MA

  • Extracellular Flux as an Indicator of Cellular Metabolism

    NAASO Annual Meeting
    October 15, 2005
    Vancouver, British Columbia

• Technology

  • Extracellular Flux Enables Real-time, Non-invasive Measurements of Cellular Metabolism

    Lab Automation 2006
    January 22, 2006
    Palm Springs, CA