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Seahorse Bioscience
Seahorse Bioscience

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Technical Posters with XF Data

Aging & Cell Stress

Testing modulators of uncoupling protein (UCP) function in intact HEK293 cells using plate-based respirometry and membrane potential sensitive fluorescent probes.

Martin Jastroch, Akos A. Gerencser, and Martin D. Brand
Buck Institute for Age Research

Molecular & Cellular Bioenergetics Gordon Research Conference
June 10, 2009
Andover, NH

Cancer

Cells addicted tp BCL-XL accumulate succinate via pyruvate carboxylase metabolism and glutaminolysis.

Daciana Margineantu and David Hockenbery, Human Biology and Clinical Research Divisions, Fred Hutchinson Cancer Research Center
AACR Metabolism & Cancer Conference
September 13-16, 2009
La Jolla, CA

Bioenergetic differences in breast cancer cell lines

Dilshan S. Harischandra and David Hockenbery, Iowa State University and Fred Hutchinson Cancer Research Center
AACR Metabolism & Cancer Conference
September 13-16, 2009
La Jolla, CA

2-Deoxyglucose Induces a Metabolic Switch to Mitochondrial Oxidative Energy Metabolism Resulting in Sensitization to Apoptosis of Glioblastoma Cells

2006 Gordon Research Conference on Cell Death
September 10-15, 2006
Big Sky Resort
Big Sky, MT

Real-time Metabolic Analysis of Glioblastoma Cells Treated with 2-Deoxyglucose Reveals a Metabolic Switch to Aerobic Energy Metabolism Mediated by HIF-1a

AACR 2006 Annual Meeting
April 1, 2006
Washington, DC

A Novel Assay for Profiling Metabolic Changes Mediated by HIF-1a in Cancer Cells

Tumor Metabolism Summit
September 19, 2005
Genoa, Italy

A Non-destructive, Time-resolved, Multi-analyte Technology for Sensing Metabolic Changes in Cancer Cells

American Association for Cancer Research
April 19, 2005
Anaheim, CA

Cardiovascular

Bioenergetics changes induced by hydrogen peroxide exposure in endothelial cells

Gloria A. Benavides, Brian P. Dranka, Brian Benoit, and Victor M. Darley-Usmar, University of Alabama at Birmingham and Seahorse Bioscience
Society for Free Radical Biology's 16th Annual Meeting
November 18 - 22, 2009
San Francisco, California

4-Hydroxy-2-Nonenal Alters Cellular Bioenergetics in Vascular Smooth Muscle Cells

Blake R. Zelickson, Anne R. Diers, Bradford G. Hill, Brian P. Dranka, Jessica Perez, Aimee Landar, and Victor M. Darley-Usmar, University of Alabama at Birmingham
Society for Free Radical Biology's 16th Annual Meeting
November 18 - 22, 2009
San Francisco, California

Direct measurement of bioenergetic stress in cardiomyocytes exposed to hydrogen peroxide and protection by O-GlcNAc

Brian P. Dranka, Bradford G. Hill, Luyun Zou, John C. Chatham, and Victor M. Darley-Usmar, University of Alabama at Birmingham
Society for Free Radical Biology's 15th Annual Meeting
November 16 - 26, 2008
Indianapolis, Indiana

Hepatobiology & In Vitro Toxicity

In vitro detection of pharmaceutical compounds that disturb mitochondrial functions

Irene Edebert, Ingalill Rafter, Ian Cotgreave; Molecular Toxicology, Safety Assessment, AstraZeneca R&D
46th Congress of the European Societies of Toxicology
September 13-16, 2009
Dresden, Germany

Neurodegeneration

Real-time monitoring of mitochondrial and cellular bioenergetics in cultured neurons in a microplate

Neuroscience 2008
Society for Neuroscience 38th Annual Meeting
November 15-19, 2008
Washington, D.C.

Obesity, Diabetes, & Metabolic Diseases

Glucose availability modulates mitochondrial sources of NADPH in skeletal muscle cells: Implications for oxidative stress

Ryan J. Mailloux and Mary-Ellen Harper, University of Ottawa
Charleston Conference on Mitochondrial Physiology and Pathobiology
November 16, 2009
Isle of Palms, North Carolina

?-Adrenergic and cAMP-Stimulated Mitochondrial Uncoupling in Human Adipocytes

Einav Yehuda-Schnaidman, Naresh Kumar, Ben Buehrer, Sheila Collins, Hamner Institute
69th Scientific Sessions of the American Diabetes Association
June 5-9. 2009
New Orleans, Louisiana

Metformin-Induced Inhibition of Mitochondrial Complex I Activity Stimulates Fatty Acid Oxidation and Glycolysis While Blunting Glucose Oxidation in C2C12 Myocytes

Molecular & Cellular Bioenergetics
June 17, 2007
Andover, New Hampshire

A Novel, Non-Radioactive Method for Measuring Fatty Acid Oxidation and Cellular Metabolism in C2C12 Myocytes

Endocrine Society 2006 Annual Meeting
June 24, 2006
Boston, MA

Extracellular Flux as an Indicator of Cellular Metabolism

NAASO Annual Meeting
October 15, 2005
Vancouver, British Columbia

Technology

Extracellular Flux Enables Real-time, Non-invasive Measurements of Cellular Metabolism

Lab Automation 2006
January 22, 2006
Palm Springs, CA