Tutorial: Measuring Bioenergetics in a Variety of Cell Types

Recent discoveries have linked mitochondrial dysfunction and defects in cellular bioenergetics to the pathophysiology of many diseases including obesity, diabetes, cancer, cardiomyopathy and neurodegeneration. The introduction of Extracellular Flux (XF) technology has enabled non-invasive, real time profiling of cellular bioenergetics and mitochondrial function in living cells, opening a new window to study these diseases.

Also discussed:

• How to prepare different cell types for XF analysis
• How to assess bioenergetic profiles of various cell types
• How to link bioenergetic profiles to cellular physiology

View On-Demand Webinar*

July 17, 2008

Event ID#113462

References and Additional Links

 

Medical University of South Carolina

Beeson Research Group

Buck Institute for Age Research

The Nicholls Lab

Contact Information

David Ferrick, Ph.D
VP, Biology & Applications, Seahorse Bioscience, Inc.
Email: dferrick@seahorsebio.com

 

Selected Publications

1. Advances in Measuring Cellular Bioenergetics using Extracellular Flux. Ferrick DA, Neilson A, and Beeson C. (2008). Drug Discov Today, in press.

2. Multiparameter Metabolic Analysis Reveals a Close Link between Attenuated Mitochondrial Bioenergetics and Enhanced Glycolysis Dependency in Human Tumor Cells.". Wu M, Neilson A, Swift AL, Moran R, Tamagnine J, Parslow D, Armistead S, Lemire K, Orrell J, Teich J, Chomicz S and Ferrick DA. (2007). Am J of Physiol Cell Physiol 292:C125-C136.

*None of the content on this website should be considered medical or psychological advice. Seahorse Biosciences does not give medical advice or diagnose medical and psychological conditions. Although every effort is made to assure that information on this site is accurate and current, knowledge in the field of cellular bioenergetics is growing rapidly and all data is subject to change without notice. You should consult with your healthcare professional for specific advice relating to your medical questions or conditions. None of the information, statements and/or links contained on the website are intended to replace the attention or medical instructions from a healthcare professional. Only your practitioner can completely and appropriately assess your situation and make conclusive decisions regarding your care.

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