Upcoming Live Webinars
We are continuing our monthly Webinar Series on Cellular Bioenergetics in 2008 with Seahorse XF technology users as guest speakers discussing their areas of expertise. We encourage you to check back regularly as we will continue to add guest speakers throughout the year or you can register to be notified via email of upcoming sessions.
May 29, 2008
1:00pmEST | 10:00amPST | 6:00pmGMT
"Protective Bioenergetic Responses of Cardiomyocytes to Hypoxic Stress"
The prolyl hydroxylase (PHD) oxygen-sensor has emerged as the central signaling pathway that mediates the cellular response to hypoxia. Elucidation of PHD-directed changes in cellular metabolism is crucial for the understanding the etiology of ischemic pathologies.
Join us for this 45-minute webinar to learn about the fundamental changes in heart cell metabolism and physiology that comprise the protective metabolic program employed against hypoxic stress.
You will learn:
• About the utility of contracting cardiomyocyte cultures in exploring the mechanisms of drugs that impact metabolic function
• The critical importance of adequate ATP turnover and workload when evaluating mitochondrial metabolism
• The mechanism via which cells down regulate ATP turnover independent from ATP synthesis
Guest Speaker:
Gary L Wright, Ph.D.
Assistant Professor, Department of Pharmaceutical Sciences, Medical University of South Carolina
Recent Webinars
"Quantifying the Mitochondrial Proton Circuit in Intact Cells - Volts and Amps"
Learn about current approaches for monitoring the proton circuit of mitochondria in situ in neurons and other cells.
Guest Speaker: David G. Nicholls, Ph.D., FRSE
Professor, Mitochondrial Dysfunction, Buck Institute for Age Research
"Thyroid Hormone Deiodination is a Key Switch for Energy Expenditure"
Learn how specific iodothyronine deiodinases can be manipulated to alter thyroid hormone signaling as a means to better understand energy homeostasis and metabolic control
Guest Speaker: Antonio C. Bianco, M.D., Ph.D.
Chief, Thyroid Section Brigham and Women’s Hospital, Associate Professor of Medicine Harvard Medical School
"Human Disorders of Bioenergetics"
Learn more about the bioenergetic basis of various diseases and some of their associated clinical findings.
Guest Speaker: Vamsi Mootha, M.D.
Department of Systems Biology, Harvard Medical School Center for Human Genetics, Massachusetts General Hospital
"Bioenergetic Consequences of Mitochondrial Fusion and Fission"
Learn how bioenergetic efficiency of the mitochondrial population within a cell may be quality controlled.
Guest Speaker: Orian Shirihai, M.D., Ph.D.
Assistant Professor of Pharmacology and Experimental Therapeutics, / Tufts University School of Medicine-Boston
"Bioenergetic and Metabolic Profiling in Drug Discovery and Safety"
Learn why bioenergetic and mitochondrial assessments should be done early in drug development and about suitable techniques amenable to drug discovery/development arenas.
Guest Speaker: James Dykens, Ph.D.
Senior Principal Scientist, Drug Safety Research & Development / Pfizer, Inc.
"Fueling Physiology: How Bioenergetics Drive Biological Function"
Learn about basic bioenergetic signatures and the importance of incorporating bioenergetics in your research or drug discovery program.
Guest Speaker: Craig Beeson, PhD
Associate Professor / Medical University of South Carolina
"Measuring Real-Time Cellular Bioenergetics"
Learn how Extracellular Flux (XF) allows you to quantify physiological changes in cellular bioenergetics by measuring the two major energy yielding pathways, mitochondrial respiration and glycolysis, in a sensitive and convenient microplate format.
Speaker: David Ferrick, PhD
VP of Biology and Applications / Seahorse Bioscience
