Technical Posters & Presentations with Seahorse XF Data

Aging

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• The Homeobox Protein Prox1 is a Negative Modulator of ERRα/PGC-1α Bioenergetic Functions

  Alexis Charest-Marcotte, Catherine R. Dufour, Brian J. Wilson, Annie M. Tremblay, Lillian J. Eichner, Daniel H. Arlow, Vamsi K. Mootha and Vincent Gigu

  Nuclear Receptors: Development, Physiology and Disease
  March 21-26, 2010
  Keystone, CO

• Testing Modulators of Uncoupling Protein (UCP) Function in Intact HEK293 Cells Using Plate-Based Respirometry and Membrane Potential Sensitive Fluorescent Probes

  Martin Jastroch, Akos A. Gerencser, and Martin D. Brand

  Molecular & Cellular Bioenergetics Gordon Research Conference
  June 10, 2009
  Keystone, CO

Cancer

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• Synergistic enhancement of 2-deoxy-D-glucose-mediated breast cancer cell death by mitochondria-targeted drugs

  Gang Cheng, Donna McAllister, Jacek Zielonka, Brian P. Dranka, Joy Joseph, Balaraman. Kalyanaraman

  Society for Free Radical Biology and Medicine (SFRBM) 2011
  November 16-20, 2011
  Atlanta, GA

• Selective killing of breast cancer cells by mitochondria-targeted alpha-tocopherol

  Jacek Zielonka, Gang Cheng, Jin-Hwan Kim, Joy Joseph, B. Kalyanaraman

  Society for Free Radical Biology and Medicine (SFRBM) 2011
  November 16-20, 2011
  Atlanta, GA

• Breast cancer, statins and 3Dcell culture

  Peter Mullen

  AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics 2011
  November 12-16, 2011
  San Francisco, CA

• The combination of statins and dipyridamole is effective preclinically in multiple myeloma, acute myelogenous leukemia and breast cancer

  A. Pandyra, P. Sobol, P.J. Mullen, A.D. Schimmer, L.Z. Penn

  AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics 2011
  November 12-16, 2011
  San Francisco, CA

• Bioenergetics of tumors: role of sequential oncogenes activation and microenvironment in the determination of cancer cells metabolic profile.

  Caroline Jose, Etienne Harbert Chatelain, Giovanni Benard, Su Melser and Rodrigue Rossignol

  Mitochondria, Apoptosis and Cancer (MAC '11)
  October 27-29, 2011
  Singapore

• Dysregulation of c-terminal ezrin phosphorylation prevents metastasis and alters cellular metabolism in osteosarcoma

  Ling Ren, Sung-Hyeok Hong, Qing-Rong Chen, Joseph Briggs, Jessica Cassavaugh, Satish Srinivasan, Narayan Avadhani, Javed Khan, Chand Khanna

  AACR Special Conference: Metabolism and Cancer 2011
  October 16-19, 2011
  Baltimore, MD

• Fenofibrate-mediated inhibition of mitochondrial respiration activates FOXO3a-BIM apoptotic pathway in human Glioblastoma cells in vitro

  Anna Wilk, Katarzyna Urbanska, David Impastato, Krzysztof Reiss

  AACR Special Conference: Metabolism and Cancer 2011
  October 16-19, 2011
  Baltimore, MD

• AMPK regulates metabolism and survival in response to ionizing radiation

  Vanessa E Zannella, Dan Cojocari, Susan Hilgendorf, Ravi N Vellanki, Stephen Chung, Bradly G Wouters, Marianne Koritzinsky

  AACR Special Conference: Metabolism and Cancer 2011
  October 16-19, 2011
  Baltimore, MD

• Novel molecular features associated with sensitivity to the anticancer effects of statins in breast tumour cells

  Carolyn A. Goard, Michelle A. Chan-Seng-Yue, Peter J. Mullen, James W. Clendening, Dorota H. S. Sendorek, Paul C. Boutros, Linda Z. Penn

  AACR Advances in Breast Cancer Research: Genetics, Biology, and Clinical Applications
  October 12-15, 2011
  San Francisco, CA

• Manipulation of lactate metabolism and radiation resistance in two human ovarian cancer cell lines

  Christian G. Fabian, Andrea Siebers, Ulrike G. A. Sattler, Wolfgang Mueller-Klieser

  14th International Congress of Radiation Research
  August 28-1, 2011
  Warsaw, Poland

• 14-3-3sigma as a new important regulator of cancer glycolysis

  Liem Phan, Ismael Samudio, Ping-Chieh Chou, Guermarie Velazquez-Torres, Hyun-Ho Choi, Edward Wang, Christopher Gully, Enrique Fuentes-Mattei

  Cold Spring Harbor Laboratory 76th Symposium of Metabolism and Disease
  June 2-3, 2011
  Cold Spring Harbor, NY

• Preclinical studies of novel phosphonium salts with broad-spectrum activity

  Melissa Millard, Divya Pathania, Yumna Shabaik, Laleh Taheri, Jinxia Deng, Nouri Neamati

  AACR Annual Meeting 2011
  April 2-6, 2011
  Orlando, FL

• Modulation of metabolic substrate uptake by the nitrosating agent, S-nitrosocysteine: Impact on bioenergetics of breast cancer cells

  Broniowska, Katarzyna

  Gordon Research Conference on Nitric Oxide
  February 13-18, 2011
  Ventura, CA

• Uptake, Subcellular Localization, Bioenergetic Effects and Antiproliferative Properties of Triphenylphosphonium‐Linked Nitroxides in Breast Cancer Cells

  Gang Cheng, Jacek Zielonka, Brian P. Dranka, Joy Joseph, Balaraman. Kalyanaraman

  Society for Free Radical Biology's 17th Annual Meeting
  November 17-20, 2010
  Orlando, FL

• Energy Metabolism and Radiosensitivity of Two HNSCC Tumor Cell Lines

  Christian G. Fabian, Wolfgang Mueller-Klieser, Ulrike G. A. Sattler

  56th Annual Meeting of the Radiation Research Society
  September 27, 2010
  Wailea, HI

• Energy Metabolism in Genetically Defined Subtypes of Diffuse Large B Cell Lymphoma

  Pilar Caro, Amar Kishan, Daniel Tondera, Alfredo Gimenez-Cassina, Margaret Shipp, Nika N. Dania

  Cancer and Metabolism: Pathways to the Future Conference
  September 19-21, 2010
  Edinburgh, Scotland

• Bioenergetic Differences in Breast Cancer Cell Lines

  Dilshan S. Harischandra and David Hockenbery

  AACR Metabolism & Cancer Conference
  September 13-16, 2009
  La Jolla, CA

• Cells Addicted to BCL-XL Accumulate Succinate via Pyruvate Carboxylase Metabolism and Glutaminolysis

  Daciana Margineantu and David Hockenbery

  AACR Metabolism & Cancer Conference
  September 13-16, 2009
  La Jolla, CA

• KSR1, a RAS-RAF-MEK Signal Cascade Protein Necessary for H-Ras-Induced Oncogenic Transformation, is Also Required for Uptake/Consumption of Glucose, Glutamine and Fatty Acid in Mouse Embryonic Fibroblasts

  Amy L. Swift, Denise Chen, Kurt Fisher, Mike Winer1, David A. Ferrick1 Robert E. Lewis and Min Wu

  American Association for Cancer Research 100th Annual Meeting
  April 9, 2009
  Denver, CO

• Real-Time Metabolic Analysis of Glioblastoma Cells Treated with 2-Deoxyglucose Reveals a Metabolic Switch to Aerobic Energy Metabolism Mediated By HIF-1a

  Min Wu, Amy Swift, Rebecca Moran and David Ferric

  American Association for Cancer Research 2006 Annual Meeting
  April 1, 2006
  Washington, DC

• A Novel Assay for Profiling Metabolic Changes Mediated By HIF-1a in Cancer Cells

  Min Wu, Amy Swift, Diane Parslow, Suzanne Armitstead, Kristie Lemire, David Ferrick

  Tumor Metabolism Summit
  September 19, 2005
  Genoa, Italy

• A Non-Destructive, Time-Resolved, Multi-Analyte Technology for Sensing Metabolic Changes in Cancer Cells

  Min Wu, Andy Neilson, Jay Teich, James Tamagnine, Diane Parslow, Kristie Lemire, Suzanne Armitstead and Steve Chomicz

  American Association for Cancer Research 2005
  April 19, 2005
  anaheim, CA

Cardiovascular

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• Snf1-related Kinase Enhances Cardiomyocyte Metabolism and Increases Mitochondrial Membrane Potential and Glycolysis Through Tribbles Homolog 3 Downreg

  Amy K. Rines, Michael A. Burke, Hossein Ardehali

  American Heart Association Scientific Sessions 2011
  November 12-16, 2011
  Orlando, FL

• Endothelial Nitric Oxide Synthase Promotes a Shift in Adipocyte Phenotype in Diet-Induced Obesity

  Brian E. Sansbury, Jason Hellmann, Yunan Tang, Kathie Nichol, Matthew Spite, Aruni Bhatnagar, and Bradford G. Hill

  American Heart Association Scientific Sessions 2011
  November 12-16, 2011
  Orlando, FL

• Manipulating Myocardial Wnt Signalling For Post-Ischemic Myocardial Protection

  K Venardos; D Williams; D Horlock; J Peart; S McGee; D Kaye

  American Heart Association Scientific Sessions 2011
  November 12-16, 2011
  Orlando, FL

• Mitochondrial Oxidative Stress Corrupts Tube Formation in Human Coronary Artery Endothelial Cells by Inhibiting mTOR Signaling

  Pung, PhD, Yuh Fen

  Arteriosclerosis, thrombosis, and vascular biology, 2011 Scientific Sessions
  April 28-30, 2011
  Chicago, IL

• Novel insights into the role of glycolysis in vascular smooth muscle cell phenotype switching

  Joshua Salabei, Aruni Bhatnagar, and Bradford G. Hill

  Experimental Biology 2011
  April 9-13, 2011
  Washington, DC, US

• Bioenergetic Dysfunction in Endothelial Cells Precedes Cell Death Due to Hemin: Implications for Hemolytic Anemias

  Ashlee N. Higdon, Gloria A. Benavides, Victor M. Darley-Usmar

  Society for Free Radical Biology's 17th Annual Meeting
  November 17-20, 2010
  Orlando, FL

• Simvastatin: The Enemy Within?

  PJ Mullen, A Zahno, S Maseneni, S Krahensbuhl, P Lindinger

  European Muscle Conference, XXXIX
  September 14, 2010
  Padua, IT

• Inhibition of Apoptosis Partially Restores Mitochondrial Function

  Gloria A. Benavides, Blake R. Zelickson, Sarah A. Owusu, Samantha Giordano, Lonnie Schneider, Brian Benoit, Jianhua Zhang and Victor M. Darley-Usmar

  5th International Conference of Neurons and Brain Disease
  June 29-1, 2010
  Bristol, GB

• Hypoxia/Reoxygenation Alters Mitochondrial Function in Endothelial Cells

  Blake R. Zelickson, Gloria A. Benavides, Aimee Landar, Jianhua Zhang, and Victor M. Darley-Usmar

  5th International Conference of Neurons and Brain Disease
  June 29-1, 2010
  Bristol, GB

• Bioenergetics Changes Induced By Hydrogen Peroxide Exposure in Endothelial Cells

  Gloria A. Benavides, Brian P. Dranka, Brian Benoit, and Victor M. Darley-Usmar

  Society for Free Radical Biology's 16th Annual Meeting
  November 18-22, 2009
  San Francisco, CA

• Direct Measurement of Bioenergetic Stress in Cardiomyocytes Exposed to Hydrogen Peroxide and Protection by O-GlcNAc

  Brian P. Dranka, Bradford G. Hill, Luyun Zou, John C. Chatham, and Victor M. Darley-Usmar

  Society for Free Radical Biology's 15th Annual Meeting
  November 16-26, 2008
  Indianapolis, IN

• Direct measurement of bioenergetic stress in cardiomyocytes exposed to hydrogen peroxide and protection by O-GlcNAc

  Brian P. Dranka, Bradford G. Hill, Luyun Zou, John C. Chatham, and Victor M. Darley-Usmar

  Society for Free Radical Biology's 15th Annual Meeting
  November 16-26, 2008
  Indianapolis, IN

Cell Physiology

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• MTCH2/MIMP: A novel regulator of liver apoptosis and metabolism

  Yehudit Zaltsman, Liat Shachnai and Atan Gross

  Cold Spring Harbor Laboratory Cell Death
  October 11-15, 2011
  Cold Spring Harbor, NY

• Quantitative Proteomics and Functional Consequences of Mitochondrial Protein Carbonylation

  Jessica Curtis, Matt Stone, Wendy Hahn, Jacob Inda, Timothy Griffin, And David Bernlohr

  Keystone Symposia on Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction
  January 13-15, 2011
  Keystone, CO

• Assessing Mitochondrial and Cellular Bioenergetics in Human Pluripotent Stem Cells

  Alessandro Prigione and James Adjay

  Targeting Mitochondria 2010
  November 18-19, 2010
  Berlin, DE

• Cellular Bioenergetics in Chicken Embryo Fibroblast (Cef) and Immortal CEF (DF-1) Cells

  K. Lassiter, J. Y. Lee, A. Piekarski , B-W. Kong, J. J. Song, and W. Bottje

  Society for Free Radical Biology's 17th Annual Meeting
  November 17-20, 2010
  Orlando, FL

• Reduction of mitochondrial reserve capacity in endothelial cells by nitric oxide and superoxide � detection and quantitation of peroxynitrite formed from co-generated NO and O2

  Jacek Zielonka, Brian P. Dranka, Monika Zielonka, Joy Joseph, Micael Hardy, Adam Sikora, and B. Kalyanaraman

  Society for Free Radical Biology's 17th Annual Meeting
  November 17-20, 2010
  Orlando, FL, US

• Abrupt Alcohol Withdrawal Suppresses Mitochondrial Repiration in an Estrogen Preventable Manner

  Xiaohua Ju, Daniel Metzger, Yi Wen, Shaohua Yang, James W. Simpkins and Marianna Jung

  Neuroscience 2010
  November 13-17, 2010
  San Diego, CA

• The Homeobox Protein Prox1 is a Negative Modulator of ERRα/PGC-1α Bioenergetic Functions

  Alexis Charest-Marcotte, Catherine R. Dufour, Brian J. Wilson, Annie M. Tremblay, Lillian J. Eichner, Daniel H. Arlow, Vamsi K. Mootha and Vincent Gigu

  Nuclear Receptors: Development, Physiology and Disease
  March 21-26, 2010
  Keystone, CO

Immunology

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• Mitochondrial dysfunction and oxidative damage in Osteoarthritis

  Christos Gavriilidis, Robert W Taylor, David A Young

  British Society for Matrix Biology Autumn Meeting, Matrix signals! Cell-matrix interactions in health and disease
  September 8-9, 2011
  Newcastle, UK

• Control of B Cell Activation and Metabolism by the voltage-Gated Proton Channel HVCN1

  Capasso, Melania

  Keystone Symposium Lymphocyte Activation and Gene Expression
  January 3, 2010
  Breckenridge, CO

Mitochondrial Diseases

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• Bioenergetics evaluation in mitochondrial disorders with the Seahorse XF96

  F. Invernizzi, I. D'Amato, P.B. Jensen, V. Tiranti and M. Zeviani

  Eighth European Meeting on Mitochondrial Pathology (EuroMIT8)
  June 20-23, 2011
  Zaragoza, Spain

• Role of Amyloid Beta in Mitochondrial Function and Dynamics in Skeletal Muscle

  Elika Shabrokh, Mattew Hulver, Madlyn Frisard

  Experimental Biology 2011
  April 9-13, 2011
  Washington, DC

Model Organisms

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Neurodegeneration

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• Mitochondrial inhibition and oxidant production differs between pharmacologic models of Parkinson's disease

  Brian P. Dranka, Jacek Zielonka, and B. Kalyanaraman

  Society for Free Radical Biology and Medicine (SFRBM) 2011
  November 16-20, 2011
  Atlanta, GA

• Inhibition of Thioredoxin Reductase potentiates paraquat-induced mitochondrial dysfunction and neurotoxicity in N27 dopaminergic cells

  Pamela Lopert and Manisha Patel

  Society for Free Radical Biology and Medicine (SFRBM) 2011
  November 16-20, 2011
  Atlanta, GA

• Reliable in vivo measurement of mitochondrial bioenergetics in animal models of temporal lobe epilepsy

  Shane Rowley and Manisha Patel

  Society for Free Radical Biology and Medicine (SFRBM) 2011
  November 16-20, 2011
  Atlanta, GA

• Partial dependence of rotenone toxicity on mitochondrial respiration: Effects of galactose versus glucose as energy sources

  April A. Dukes and Teresa G. Hastings

  Neuroscience 2011
  November 12, 2011
  Washington DC

• Assessment of caprylic triglyceride for dietary intervention in an amyotrophic lateral sclerosis mouse model

  M. VARGHESE, W. ZHAO, P. VEMPATI, A. CHENG, G. M. PASINETTI

  Neuroscience 2011
  November 12, 2011
  Washington DC

• Preclinical efficacy of 2-Deoxyglucose to sustain mitochondrial metabolic function and delay progression of Alzheimer's pathology

  Jia YAO, Shuhua Chen, ZisuMao, Fan Ding, Enrique Cadenas, Roberta Diaz BRINTON

  Neuroscience 2011
  November 12, 2011
  Washington DC

• Mutations in ATP13A2 impact on mitochondrial function and morphology

  B. Arns, P. Seibler, A. Rakovic, A. Ramirez, C. Sue, C. Klein, A. Grünewald

  84th Congress of the German Society of Neurology (DGN)
  September 28-1, 2011
  Wiesbaden, DE

• Stimulation of mitochondrial motility in hippocampal neurons improves neurite distribution and bioenergetic capacity

  A. Ferree, A. Newby-Kew, K. Tradeau, E. Zik, V. Levy, B. Wolozin, P. Lansbury, O. Shirihai

  Mitochondrial Dynamics: From Mechanism to Disease
  September 11-15, 2011
  Sartinia, IT

• SCaMC-3, The Brain and Liver Mitochondrial ATP-Mg/Pi Transporter, Prevents Mitochondrial Damage During Excitotoxicity Insults in vitro and in vivo by

  Rueda CB, Traba J, Amigo I, Pardo B, del Arco A, Satrustegui J

  Gordon Research Conference on Calcium Signalling
  June 26-1, 2011
  Waterville Valley, ME

• The Effects of Idebenone on Mitochondrial Bioenergetics

  Valentina Giorgio, Valeria Petronilli, Anna Ghelli, Valerio Carelli, Michela Rugolo & Paolo Bernardi

  Eighth European Meeting on Mitochondrial Pathology (EuroMIT8)
  June 20-23, 2011
  Zaragoza, Spain

• DNA Damage Precedes Cell Death in Rotenone Rat Model of Parkinson's Disease

  L.H. Sanders, P. G. Mastroberardino, V. Tapias, X. Hu, C.T. Chu, J.T. Greenamyre

  Society for Free Radical Biology's 17th Annual Meeting
  November 17-20, 2010
  Orlando, FL

• Overexpression of The Neuron-Specific Drp1 Isoform that Includes Exon 3 (ISO1) Increases Mitochondrial Respiratory Capacity in Neurons

  C.A. Danilov, T. Uo, D.H. Margineantu, D. Hockenbery and R.S. Morrison

  Neuroscience 2010
  November 13-17, 2010
  San Diego, CA

• Neuronal Bioenergetic Reserves: Importance in Parkinson's Disease

  Brian P. Dranka, Anumantha G. Kanthasamy, B. Kalyanaraman

  Neuroscience 2010
  November 13-17, 2010
  San Diego, CA

• Dj-1 Knock-Down Impairs Astrocyte Mitochondrial Function

  N.J. Larsen, G. Ambrosi, S.J. Mullett, S.B. Berman, D.A. Hinkle

  Neuroscience 2010
  November 13-17, 2010
  San Diego, CA

• Decreased Respiratory Capacity and Glycolytic Rates in a Rat Model of Temporal Lobe Epilepsy Revealed by Metabolic Flux Analysis of Hippocampal Synaptosomes

  Shane Rowley and Manisha Patel

  Neuroscience 2010
  November 13-17, 2010
  San Diego, CA

• Real-Time Monitoring of Mitochondrial and Cellular Bioenergetics in Cultured Neurons in a Microplate

  Amy L. Swift, Etienne Regulier, Younga Shin, Nagendra Yadava, David Nicholls, David A. Ferrick and Min Wu

  Neuroscience 2008: Society for Neuroscience 38th Annual Meeting
  November 15-19, 2008
  Washington, DC

Obesity, Diabetes & Metabolic Disorders

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• Mitochondrial dynamics play a key role in brown adipocyte activation

  Jakob D Wikstrom, Samuel B Sereda, Yaguang Si, Marc Liesa, Guy Las, Gilad Twig, Kiana Mahdaviani, Barbara Corkey, Barbara Cannon, Jan Neder

  Mitochondrial Physiology and Medicine
  September 7-11, 2011
  Woods Hole, MA

• Selective over expression of toll-like receptor 4 in skeletal muscle causes impaired adaptation to high-fat feeding

  Ryan McMillan, Yaru Wu, Kevin Voelker, John Kavanaugh, Kristin Wahlberg, Angela Anderson, Kim Haynie, Madlyn Frisard, and Matthew Hulver

  American Diabetes Association 71st Scientific Sessions
  June 24-28, 2011
  San Diego, CA

• Selective over expression of toll-like receptor 4 in skeletal muscle causes impaired adaptation to high-fat feeding

  Ryan McMillan, Yaru Wu, Kevin Voelker, John Kavanaugh, Kristin Wahlberg, Angela Anderson, Kim Haynie, Madlyn Frisard, and Matthew Hulver

  American Diabetes Association 71st Scientific Sessions
  June 24-28, 2011
  San Diego, CA

• Deletion of the Mitochondrial Transcription Factor A (TFAM) in Adipose Tissue Causes Mitochondrial Dysfunction and Protects Mice from Obesity and Insulin Resistance

  Vernochet, PhD, Cecile

  American Diabetes Association 71st Scientific Sessions
  June 24-28, 2011
  San Diego, CA

• The role of toll-like receptor 4 in mitochondrial function and reactive oxygen species (ROS) production in skeletal muscle

  Yaru Wu, Madlyn Frisard, Elike Shabrokh, Kevin Voelker, Ryan P McMilian, Matthew W Hulver

  Experimental Biology 2011
  April 9-13, 2011
  Washington, DC

• Effect of Diabetes Mellitus on Mitochondrial Oxygen Consumption in Peripheral Blood Mononuclear Cells

  Hartman M, Levy V, Xu G, Frame A, Caiano T, Kluge M, Tabit C, Dohadwala M, Shah A, Kocherla M, Levitt A, Kim B, Duess M, Shenouda S, Holbrook M, Hambu

  D-Cure's 5th Annual Symposium
  March 29-30, 2011
  Tel Aviv, Israel

• The CREB Coactivators, Crtc2 and Crtc3 Function as Exercise Mimetics in Skeletal Muscle

  Nelson E. Bruno, Antonio L. Ameilo, Mariam B. Lawani and Michael D. Conkright.

  Keystone Symposia on Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction
  January 13-15, 2011
  Keystone, CO

• HSP72 Preserves Insulin Sensitivity and Prevents Peripheral Tissue Lipotoxicity By Increasing Oxidative Metabolism in Skeletal Muscle

  DC Henstridge, CR Bruce, BG Drew, N Watson, J Chung, V Ribas, SW Beaven, MJ Watt, M Hargreaves, SL McGee, MA Febbraio, AL Hevener

  Keystone Symposia on Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction
  January 13-15, 2011
  Keystone, CO

• Class IIa Histone Deacetylases Contribute to Skeletal Muscle Transcriptional and Metabolic Remodeling and Oxidative Stress in Insulin Resistance

  Courtney Swinton, Shona Morrison, Tim Connor, Ken Walder, Greg R. Steinberg, Mark Hargreaves and Sean L. McGee

  Keystone Symposia on Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction
  January 13-15, 2011
  Keystone, CO

• Chronic Hyperglycemia-Induced Attenuation of Mitochondrial Reserve Capacity Mediates Mesangial Cell Dysfunction in Diabetes

  Balu K Chacko, Colin Reily, Gloria A Benavides, Michelle S. Johnson, and Victor M. Darley-Usmar

  Society for Free Radical Biology's 17th Annual Meeting
  November 17-20, 2010
  Orlando, FL

• Differential Regulation of Metabolic Pathways By Snitrosation in Endothelial Cells

  Anne R. Diers, Katarzyna A. Broniowska and Neil Hogg

  Society for Free Radical Biology's 17th Annual Meeting
  November 17-20, 2010
  Orlando, FL

• The Mesodermal Developmental Gene Tbx15 Regulates Triglyceride Accumulation and Mitochondria Respiration in Adipocytes

  Gesta, Stephane

  Obesity 2010
  October 11, 2010
  San Diego, CA

• Islet Respiratory Leak is Acutely Regulated by Nutrients and ROS and is Dysregulated in the Obese State

  Jakob D Wikstrom, Alvaro Elorza, Emma M Allister, Samuel B Sereda, Linsey Stiles, Andy Neilson, David A Ferrick, Michael B Wheeler, Shaoping Deng, Orian S Shirihai

  European Association for the Study of Diabetes Annual Meeting
  September 20-24, 2010
  Stockholm, Sweden

• Brown Adipocyte Activation is Characterized By a Wave of Mitochondrial Fission and Depolarization That is Dependent On β3 Receptor Stimulation and Drp1, and is Characterized By Complete, But Reversible, Arrest of Fusion

  Samuel B Sereda, Jakob D. Wikstrom, Yaguang Si, Gilad Twig, Marc Liesa, Guy Las, Cannon B, Nedergaard J, and Orian S. Shirihai

  Brown Adipose Tissue and Human Obesity Conference
  July 10, 2010
  Stockholm, Sweden

• Sirt3, a Novel Regulator of Mitochondrial Function and Insulin Signaling in Diabetes and Insulin Resistant States

  Jing, Enxuan

  ADA 70th Scientific Sessions
  April 26-28, 2010
  Orlando, FL

• The Homeobox Protein Prox1 is a Negative Modulator of ERRα/PGC-1α Bioenergetic Functions

  Alexis Charest-Marcotte, Catherine R. Dufour, Brian J. Wilson, Annie M. Tremblay, Lillian J. Eichner, Daniel H. Arlow, Vamsi K. Mootha and Vincent Gigu

  Nuclear Receptors: Development, Physiology and Disease
  March 21-26, 2010
  Keystone, CO

• Glucose Availability Modulates Mitochondrial Sources of NADPH in Skeletal Muscle Cells: Implications for Oxidative Stress

  Ryan J. Mailloux and Mary-Ellen Harper

  Charleston Conference on Mitochondria Physiology and Pathobiology
  November 16, 2009
  Isle of Palms, NC

• Novel Islet Respirometry Assay Reveals High Levels of Uncoupled Respiration in Islets

  Jakob Wikstrom, Alvaro Elorza, Emma M Allister, Samuel B Sereda, Linsey Stiles, Andy Neilson, David A Ferrick, Michael B Wheeler, Shaoping Deng, Orian S Shirihai

  Charleston Conference on Mitochondria Physiology and Pathobiology
  November 16, 2009
  Isle of Palms, NC

• Loss of mitochondrial fusion protein in the beta-cell leads to diabetes, obesity, and islet hyperplasias

  Molina, Anthony

  69th Scientific Sessions of the American Diabetes Association
  June 5-9, 2009
  New Orleans, LA

• [Beta]-Adrenergic and cAMP-Stimulated Mitochondrial Uncoupling in Human Adipocytes

  Einav Yehuda-Shnaidman, Naresh Kumar, Ben Buehrer, Sheila Collins

  69th Scientific Sessions of the American Diabetes Association
  June 5-9, 2009
  New Orleans, LA

• Metformin-Induced Inhibition of Mitochondrial Complex I Activity Stimulates Fatty Acid Oxidation and Glycolysis While Blunting Glucose Oxidation in C2C12 Myocytes

  Min Wu, Amy L. Swift, Rebecca Moran and David A. Ferrick

  Gordon Research Conference: Molecular & Cellular Bioenergetics
  June 17, 2007
  Andover, NH

• A Novel, Non-Radioactive Method for Measuring Fatty Acid Oxidation and Cellular Metabolism in C2C12 Myocytes

  Mark E. Rothenberg, Tina Patel, Chris Braun, Suzanne Armitstead, Kristie Lemire, Rebecca Moran, Craig Beeson, David A. Ferrick

  Endocrine Society 2006 Annual Meeting
  June 24, 2006
  Boston, MA

• Extracellular Flux as an Indicator of Cellular Metabolism

  Chris Braun, Mark Rothenberg, Suzanne Armitstead, Kristie Lemire, Diane Parslow, Tina Patel, and David Ferrick

  NAASO Annual Meeting
  October 15, 2005
  Vancouver, BC, CA

Screening

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• Analysis of glycolytic flux as a rapid screen to identify low lactate producing CHO cell lines with desirable monoclonal antibody yield and glycan profile

  Legmann R, Melito J, Belzer I, Ferrick D

  ESACT (European Society for Animal Cell Technology)
  May 15-18, 2011
  Vienna Austria

Stem Cell Biology

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• Assessing Mitochondrial and Cellular Bioenergetics in Human Pluripotent Stem Cells

  Alessandro Prigione and James Adjay

  Targeting Mitochondria 2010
  November 18-19, 2010
  Berlin, DE

Technology

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• Analysis of glycolytic flux as a rapid screen to identify low lactate producing CHO cell lines with desirable monoclonal antibody yield and glycan profile

  Legmann R, Melito J, Belzer I, Ferrick D

  ESACT (European Society for Animal Cell Technology)
  May 15-18, 2011
  Vienna Austria

• Extracellular Flux Enables Real-Time, Non-Invasive Measurements of Cellular Metabolism

  David Ferrick, Mark Rothenberg, Min Wu, Chris Braun

  Lab Automation 2006
  January 22, 2006
  Palm Springs, CA

• A Novel Assay for Profiling Metabolic Changes Mediated By HIF-1a in Cancer Cells

  Min Wu, Amy Swift, Diane Parslow, Suzanne Armitstead, Kristie Lemire, David Ferrick

  Tumor Metabolism Summit
  September 19, 2005
  Genoa, Italy

Toxicology & Hepatobiology

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