XF Bioenergetic Applications Provide a New Window on Cell Metabolism

Energy Pathways

Seahorse XF instruments measure energy utilization in living cells, simultaneously quantifying mitochondrial respiration and glycolysis in real time. The technology offers a robust and simple method for studying substrate utilization, mitochondrial function, energy expenditure and cell quality in microplates, without the use of large number of cells, flasks, electrodes, dyes, radioactive materials or lysis of cells that is typical of other methods.

The XF analyzer's unique ability to measure the metabolic phenotype of cells by simultaneously measuring respiration and glycolysis in real-time, and the shift between the two pathways under pathological states, enables you to connect physiological traits of cells with genomic and proteomic data to generate new insights into obesity, diabetes, cancer, cardiovascular and neurodegenerative function and safety toxicity.