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Applications in Model Organisms

Models are those organisms with a wealth of biological data that make them attractive to study as examples for other species – including humans – that are more difficult to study directly. In the arena of drug discovery, model organisms provide an inexpensive and relatively quick means to perform two main functions: target identification and target validation. Together, these help show the value of any specific therapeutic strategies and drugs when attempting to reduce disease severity.

The XF Analyzer generates data that can provide new understanding in relation to model organisms and mitochondrial dysfunction, by allowing the measurement of cellular metabolism in real-time, in a microplate. By measuring the oxygen consumption rate (OCR) - a measure of mitochondrial respiration; as well as the extracellular acidification rate (ECAR) - a measure of glycolysis, you will be provided with the most physiologically relevant in vitro measurement for your bioenergetic studies.

• Aging
• Cancer
• Cardiovascular
• Cell Physiology
• Immunology
• Mitochondrial Diseases
• Model Organisms
• Neurodegeneration
• Obesity, Diabetes, & Metabolic Disorders
• Screening
• Stem Cell Biology
• Toxicology & Hepatobiology
• Translational Medicine